methyl methacrylate health effects

keywords = "Cross-sectional study, Methyl methacrylate, Nervous system, Pulmonary function, Subjective symptoms". English-language studies on occupational hazards of MMA in the healthcare setting with evidence level IV or higher were included. Methyl Methacrylate (MMA) Use of MMA in Nail Products Environmental Health Guide What is MMA? Recommendations for occupational safety and health: compendium of policy documents and statements. 1979;50(3):451–8. For instance, McLaughlin and colleagues subjected pregnant mice to concentrations of 1330 ppm for 2 h twice daily for 10 days, whereas the OSHA recommends a maximum exposure of 100 ppm over 8 h [17]. Lin, J.S., Townsend, J.A., Humbyrd, C. et al. We performed a systematic review of studies on effects that MMA may have in pregnancy in the context of exposure during orthopaedic surgery and dentistry. Despite the data from these aforementioned studies, it has been shown that female orthopaedic surgeons have higher rates of complications in pregnancy, such as increased rates in infertility, preterm labor, preterm delivery, and incidence of congenital anomalies compared to the general United States female population [18, 19]. Methyl methacrylate ( MMA) is an organic compound with the formula CH 2 =C(CH 3 )COOCH 3. AU - Etoh, Norihito. Singh et al [9] intra-peritoneally injected MMA into pregnant rats, and reported dose-related increases in external malformations as well as reduced weight in the fetuses. 4. In a follow-up of this study, and in an additional study on workers employed in the same types of operations, but after 1945 and at different plant sites, no increased risk of cancer was observed. Hamilton AR, Tyson MD, Braga JA, Lerner LB. Product name : Methyl Methacrylate Monomer CAS-No. The authors independently confirmed the search on November 27, 2019. The conclusions of the clinical studies are limited, as the retrospective cohort studies [12, 14] are not able to control for MMA exposure specifically among other agents in the dental workplace. In addition, the two clinical studies by Linehan et al. Found inside – Page 1-326Division Surveillance , Hazard Evaluations , and Field Studies . III . Title . 77-1878 HE 20.7102 : M 56/2 Cromer , John . study of methyl methacrylate exposures and employee health / John Cromer , Kenneth Kronoveter . 2006;88(9):1957–61. The mixing is a timed and precise procedure and after mixing,the cement has to be used within ... adverse health effects because of individual susceptibility, a pre-existing medical condition, and/or a hypersensitivity (allergy). 1985. Methyl methacrylate CASRN 80-62-6 | DTXSID2020844. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. It is a volatile, colorless liquid that has a strong, sharp, distinctive odor. NIOSH: The recommended airborne exposure limit (REL) is 2 ppm averaged over a 10-hour workshift. On either day 5, 10, or 15 of gestation, the authors performed intraperitoneal injections of methacrylate esters, including MMA, at a tenth, fifth, or a third of its acute intraperitoneal lethal dose (LD50). The effect observed most frequently at lowest concentration after repeated inhalation exposure to methyl methacrylate is irritation of the nasal cavity. Also, always do your own research on a product’s ingredients by using a resource such as the Environmental Working Group’s Skin Deep product database. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Methyl methacrylate (MME) is commonly found in healthcare facilities in surgical bone cement. The MMA monomer is a colorless, pungent liquid metabolized to methacrylic acid, with described toxicities to various tissues [3, 4]. The effect observed most frequently at lowest concentration after repeated inhalation exposure to methyl methacrylate is irritation of the nasal cavity. Similarly, the American Conference of Governmental Industrial Hygienists recommends a limit of 50 ppm over an eight-hour period with 100 ppm as the peak exposure limit [6]. Nine studies were identified for inclusion. After sacrifice, the fetuses were examined morphologically, and the authors did not detect any difference in abnormalities, fetal resorptions, or fetal deaths between exposed mothers and controls. A nail professional is exposed to dust and fumes for several hours during each working day. During simulated total hip arthroplasty with vacuum mixing of cement in a hood, the mean peak exposure for the surgeon and scrub technician was 8.4 ppm and 19.5 ppm, respectively, and levels returned to baseline of < 1 ppm at a mean of 8.4 min and 11 min, respectively. Muttray A, Gosepath J, Brieger J, Faldum A, Zagar C, Mayer-Popken O, et al.

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